Paracetamol (AMCETAM) 150mg/mL Ampoule 10’s

Paracetamol (AMCETAM) 150mg/mL Ampoule

About the Product

Paracetamol (AMCETAM) 150mg/mL Ampoule is a fast-acting, injectable formulation of paracetamol designed for intravenous (IV) or intramuscular (IM) administration. It delivers effective analgesic (pain-relieving) and antipyretic (fever-reducing) action for patients who require rapid therapeutic response and for whom oral administration is not feasible. This formulation is commonly used in clinical, hospital, and emergency settings, particularly for patients undergoing surgery, suffering from high fevers, or experiencing acute pain.

Paracetamol, also known as acetaminophen, is one of the most widely used medications worldwide for the relief of mild to moderate pain and the reduction of fever. It is often preferred due to its strong safety profile and effectiveness when used correctly. The injectable form, Paracetamol (AMCETAM) 150mg/mL Ampoule, is especially useful in scenarios such as post-operative care, intensive care units, pediatric wards, and other critical care environments where quick onset of action is required.

---

Indications

Paracetamol (AMCETAM) 150mg/mL Ampoule is indicated for:

• Post-Operative Pain Relief
  Provides fast and effective reduction of pain and discomfort following surgical procedures. Commonly used as part of multimodal analgesia.

• Fever Management in Acute Settings
  Ideal for reducing high-grade fevers, especially when oral medications are contraindicated or not tolerated.

• Acute Pain Control
  Effective in managing pain related to trauma, inflammation, or medical emergencies such as severe headaches and musculoskeletal pain.

• Pediatric and Geriatric Use
  Appropriate for use in infants, children, and elderly patients when oral intake is not possible, under strict medical supervision.

• Critical Care and Emergency Settings
  Frequently administered in intensive care units (ICUs), emergency departments, and during transport for rapid symptom relief.

---

Dosage and Administration

The dosage of Paracetamol (AMCETAM) 150mg/mL Ampoule should always be determined by a healthcare professional based on the patient’s age, weight, clinical condition, and liver function status.

Adults and Adolescents (≥50 kg):

• Recommended dose: 1,000 mg (i.e., two 150mg/mL ampoules in 2 mL total), up to 4,000 mg per day, divided into several doses.

• Dosing interval: Every 4 to 6 hours as needed, ensuring minimum intervals between doses.

Adults and Children (<50 kg):

• Dose calculated based on 15 mg/kg per dose.

• Maximum daily dose: Should not exceed 60 mg/kg/day, up to a total of 3,000 mg in 24 hours.

Infants and Neonates:

• Strictly administered under medical supervision with dose adjusted according to weight and clinical assessment.

Patients with Hepatic Impairment:

• Lower doses are recommended due to the increased risk of hepatotoxicity.

• Careful monitoring of liver function and cumulative daily dose is necessary.

---

Usage Guidelines

• Administer via slow intravenous infusion over at least 15 minutes or as an intramuscular injection depending on clinical need.

• Ensure accurate dosage calculation, particularly in pediatric and low-weight patients.

• Avoid co-administration with other medications containing paracetamol to prevent cumulative overdose.

• Monitor liver function in long-term use or in patients with pre-existing liver disease.

• Regularly evaluate therapeutic response, especially in critically ill or post-operative patients.

---

Side Effects

Paracetamol (AMCETAM) 150mg/mL Ampoule is generally well tolerated, especially when administered correctly. However, potential side effects include:

• Common:

  • Local irritation or pain at the injection site

  • Nausea and occasional vomiting

  • Mild changes in liver enzymes (transient)

• Rare:

  • Hypersensitivity reactions (rash, hives, pruritus)

  • Hepatotoxicity in case of overdose or in patients with liver disease

  • Hypotension (low blood pressure) after IV administration

  • Blood disorders (very rare and usually with prolonged use)

Severe adverse reactions should be reported to a physician immediately, and supportive treatment should be initiated if necessary.

---

Precautions and Warnings

• Liver Disease: Use with caution in patients with impaired hepatic function. Avoid in cases of severe liver impairment unless deemed essential.

• Pregnancy and Lactation: Safe under medical guidance; consult a healthcare provider before use.

• Drug Interactions: Be cautious when combining with other medications that contain paracetamol to avoid overdose. May interact with anticoagulants such as warfarin with prolonged use.

• Alcohol Consumption: Concurrent use of alcohol increases the risk of liver toxicity and should be avoided.

• Renal Impairment: Monitor renal function in long-term or high-dose use.

---

Storage Instructions

• Store Paracetamol (AMCETAM) 150mg/mL Ampoule at controlled room temperature (15°C to 30°C).

• Protect from light and moisture. Do not freeze.

• Ensure the ampoule is sealed and intact before administration.

• Keep out of reach of children and unauthorized individuals.

• Dispose of any unused or expired ampoules according to medical waste disposal protocols.

---

Conclusion

Paracetamol (AMCETAM) 150mg/mL Ampoule is a reliable and essential medication for fast-acting relief of pain and fever in both routine and critical care settings. Its injectable formulation offers flexibility and rapid absorption, making it an ideal option for patients who cannot take oral medication. When administered by qualified medical professionals and under appropriate supervision, AMCETAM delivers effective results with a strong safety profile.

---

For more information about Paracetamol (AMCETAM) 150mg/mL Ampoule, including usage guidelines, availability, and clinical support, please contact your local distributor or healthcare provider.