About the Product – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

Methylprednisolone (METPREZ 16) 16mg Tablet 100’s is a potent corticosteroid used to manage a wide range of inflammatory, allergic, autoimmune, and immune-mediated conditions. Each tablet contains 16mg of Methylprednisolone, a synthetic glucocorticoid that reduces inflammation by inhibiting multiple inflammatory cytokines and suppressing the immune response.

Formulated under the METPREZ brand, this high-strength corticosteroid is ideal for moderate to severe conditions requiring systemic corticosteroid therapy, including rheumatoid arthritis, lupus, asthma, ulcerative colitis, severe allergic reactions, and dermatologic diseases. It is also used in acute flare-ups of chronic diseases or as part of organ transplant and oncology protocols.

The 100-tablet pack is suitable for hospital use, rheumatology and pulmonology clinics, and long-term management under medical supervision.

Indication – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

Methylprednisolone (METPREZ 16) is indicated for the treatment of:

• Autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis

• Allergic conditions including severe asthma, anaphylaxis, and allergic rhinitis

• Dermatologic disorders like psoriasis, eczema, and severe dermatitis

• Inflammatory bowel diseases including ulcerative colitis and Crohn’s disease

• Endocrine disorders such as adrenal insufficiency

• Neurological disorders like multiple sclerosis flares

• Adjunctive treatment in cancer, organ transplants, and shock management

Usage – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

Use only as directed by a healthcare professional. Dosage is highly individualized based on the patient’s condition, severity, and treatment response.

Typical dosing:

• Adults: 4mg to 48mg daily in divided doses or as a single daily dose

• High-dose therapy may be used short-term for acute flares or life-threatening conditions

• Tapering may be required after prolonged use to avoid adrenal suppression

Instructions for Use:

• Take orally with food to minimize gastrointestinal irritation

• Follow physician’s instructions closely, especially regarding tapering schedules

• Do not stop abruptly after long-term use

Contraindications – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

Do not use in patients with:

• Systemic fungal infections

• Known hypersensitivity to methylprednisolone or other corticosteroids

• Live or live-attenuated vaccinations during high-dose therapy

Precautions – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

Use with caution in patients with:

• Diabetes mellitus (may increase blood glucose levels)

• Hypertension or heart failure (risk of fluid retention)

• Osteoporosis or risk of bone loss

• History of peptic ulcer or GI bleeding

• Infections – corticosteroids may mask symptoms or worsen infections

Long-term use requires monitoring for Cushingoid symptoms, bone density, glucose, blood pressure, and electrolytes.

Possible Side Effects – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

Common side effects:

• Increased appetite and weight gain

• Mood changes, insomnia

• High blood sugar

• Fluid retention and swelling

Serious effects:

• Osteoporosis, fractures

• Peptic ulcers or GI bleeding

• Immunosuppression and increased infection risk

• Adrenal suppression or Cushing’s syndrome

Seek medical help for persistent or severe side effects, or signs of infection or vision changes.

Storage – Methylprednisolone (METPREZ 16) 16mg Tablet 100’s

• Store at room temperature (20°C to 25°C)

• Keep away from moisture, heat, and direct sunlight

• Keep in original blister or container

• Keep out of reach of children

• Do not use expired medication