Losartan (LOSAAR 100) 100 mg tablet 100s Lot No 250646 EXP 6/30/2028

About Losartan (LOSAAR 100) 100mg Tablet 100’s

Losartan (LOSAAR 100) 100mg Tablet 100’s is an angiotensin II receptor antagonist (ARB) used primarily to treat high blood pressure (hypertension) and certain heart-related conditions. Losartan works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. By inhibiting its effects, Losartan helps relax and widen the blood vessels, making it easier for the heart to pump blood and reducing blood pressure.

Indications:

Losartan (LOSAAR 100) 100mg Tablet 100’s is indicated for the following conditions:

• Hypertension (High Blood Pressure):
  • Losartan is used to lower blood pressure in adults and children (6 years and older), which helps reduce the risk of stroke, heart attack, and kidney problems associated with high blood pressure.
• Heart Failure:
  • Used in patients with heart failure to help improve symptoms and reduce the need for hospitalization.
• Chronic Kidney Disease (Diabetic Nephropathy):
  • In patients with type 2 diabetes and evidence of diabetic nephropathy (kidney damage), Losartan helps protect kidney function.
• Stroke Risk Reduction:
  • Losartan may be used to reduce the risk of stroke in patients with high blood pressure and left ventricular hypertrophy (an enlargement of the heart’s left ventricle).

Dosages:

The typical dosage of Losartan (LOSAAR 100) 100mg Tablet 100’s varies based on the condition being treated and individual patient factors. Below are common dosages:

• Hypertension (High Blood Pressure):
  • Adults: The usual starting dose is 50 mg once daily. Depending on the patient’s response, the dose may be increased to 100 mg once daily. In some cases, it may be combined with a diuretic (e.g., Hydrochlorothiazide).
  • Children (6 to 16 years old): The usual starting dose is 0.7 mg/kg once daily, up to a maximum of 50 mg daily.
• Heart Failure:
  • Adults: The recommended dose is 50 mg once daily, and it can be gradually increased to 100 mg once daily, depending on the patient’s tolerance and response.
• Diabetic Nephropathy (Chronic Kidney Disease in Diabetes):
  • Adults: The starting dose is typically 50 mg once daily, which can be adjusted based on blood pressure and kidney function to a maximum of 100 mg daily.
• Stroke Risk Reduction:
  • Adults: The starting dose is typically 50 mg once daily, with the potential to increase to 100 mg once daily.

Side Effects:

Like all medications, Losartan (LOSAAR 100) 100mg Tablet 100’s may cause side effects. Most people tolerate it well, but some may experience the following:

• Common side effects:
  • Dizziness or lightheadedness (especially when standing up quickly)
  • Fatigue
  • Headache
  • Nasal congestion or cold-like symptoms
  • Elevated potassium levels (hyperkalemia)
  • Diarrhea
• Serious side effects (less common):
  • Low blood pressure (hypotension): Especially if starting treatment or if used with other blood pressure-lowering medications.
  • Kidney dysfunction: Symptoms may include changes in urine output, swelling in the legs or ankles, or weight gain.
  • Elevated potassium levels (hyperkalemia): High potassium can cause muscle weakness, irregular heart rhythms, or other serious issues.
  • Allergic reactions: Swelling of the face, lips, tongue, or throat, which may cause difficulty breathing (angioedema). This is a rare but serious reaction and requires immediate medical attention.
• Very rare but serious side effects:
  • Liver problems: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, or unusual fatigue.
  • Fetal harm: Losartan is not recommended during pregnancy (especially in the second and third trimesters), as it may harm the developing fetus.

Contraindications:

Losartan (LOSAAR 100) 100mg Tablet 100’s should not be used in the following conditions:

• Hypersensitivity: If you are allergic to Losartan or any of the excipients (inactive ingredients) in the tablet, it should not be used.
• Pregnancy: Losartan is contraindicated during pregnancy, particularly during the second and third trimesters, as it can cause injury or death to the fetus.
• Severe Liver Impairment: Losartan is contraindicated in patients with severe liver disease or hepatic impairment.
• Bilateral Renal Artery Stenosis (narrowing of both kidneys’ arteries): It should not be used in patients with a history of bilateral renal artery stenosis or in patients with a single kidney.
• Hypotension (Severe Low Blood Pressure): Losartan (LOSAAR 100) 100mg Tablet 100’s should be avoided in patients with severe hypotension or volume depletion.
• Hyperkalemia: If you have high potassium levels, Losartan should not be used as it can exacerbate the condition.

Warnings and Precautions:

• Kidney Function Monitoring: Regular monitoring of kidney function is important, particularly in patients with pre-existing kidney conditions or those taking other medications that may affect renal function.
• Electrolyte Imbalance: Losartan (LOSAAR 100) 100mg Tablet 100’s may cause elevated potassium levels, so regular blood tests to monitor electrolytes are necessary.
• Pregnancy and Breastfeeding: Losartan (LOSAAR 100) 100mg Tablet 100’s should not be used during pregnancy, and breastfeeding is not recommended while taking this medication.
• Use with Caution in Elderly Patients: Elderly patients may be more sensitive to the blood pressure-lowering effects of Losartan and may require careful dose adjustments.
• Dehydration or Volume Depletion: If you are dehydrated or have reduced blood volume (due to diarrhea, vomiting, or excessive use of diuretics), Losartan may cause a significant drop in blood pressure. This should be corrected before starting treatment.

Storage:

• Store Losartan (LOSAAR 100) 100mg Tablet 100’s at room temperature (between 15°C and 30°C), away from moisture, heat, and light.
• Keep out of reach of children.

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