About Irbesartan (IRBEQ) 300mg Tablet 

Irbesartan (IRBEQ) 300mg Tablet 100’s is an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension) and protect the kidneys from damage due to diabetes. Each tablet contains 300mg of Irbesartan, a potent antihypertensive agent that works by relaxing blood vessels, allowing blood to flow more easily, thereby reducing blood pressure and easing the heart’s workload.

Manufactured to high pharmaceutical standards, IRBEQ is indicated for long-term management of essential hypertension in adults, either alone or in combination with other antihypertensive agents such as hydrochlorothiazide or calcium channel blockers. It is also prescribed for patients with type 2 diabetes and hypertension, particularly when there’s evidence of kidney involvement, as Irbesartan slows the progression of nephropathy.

Irbesartan works by selectively blocking the angiotensin II receptor subtype 1 (AT1), preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II, a hormone that narrows blood vessels and increases blood pressure. Unlike ACE inhibitors, ARBs like Irbesartan do not interfere with bradykinin metabolism, reducing the risk of dry cough and angioedema.

Indications of Irbesartan (IRBEQ) 300mg Tablet 100’s

• Essential hypertension: First-line treatment for lowering high blood pressure in adults.
• Diabetic nephropathy: In patients with type 2 diabetes and hypertension, especially with proteinuria (microalbuminuria or overt proteinuria).
• Cardiovascular risk reduction: May reduce the risk of stroke and other heart complications when blood pressure is effectively controlled.

Dosage and Administration of Irbesartan (IRBEQ) 300mg Tablet 

• The usual starting dose is 300 mg once daily.
• Maximum dose: 300 mg once daily.
• Can be taken with or without food.
• Dose adjustment may be needed in patients with volume depletion or renal impairment.
• May be used in combination with diuretics or other antihypertensives.

Note: Dosage must be determined by a physician based on individual health status and treatment goals.

 

Contraindications of Irbesartan (IRBEQ) 300mg Tablet 100’s

• Hypersensitivity to Irbesartan or any of its components
• Pregnancy (especially during the 2nd and 3rd trimesters) is known to cause injury and death to the developing fetus
• Severe hepatic impairment
• Concomitant use with aliskiren in patients with diabetes or renal impairment (eGFR < 60 mL/min/1.73 m²)

Side Effects of Irbesartan (IRBEQ) 300mg Tablet 

Common:

• Dizziness or lightheadedness
• Fatigue
• Hyperkalemia (high potassium levels)
• Nausea

Less common but serious:

• Hypotension (especially in volume-depleted individuals)
• Renal dysfunction
• Angioedema (rare)
• Elevated liver enzymes

Precautions of Irbesartan (IRBEQ) 300mg Tablet 

• Monitor renal function and potassium levels regularly, especially in patients with kidney disease or on potassium-sparing medications.
• Use caution in patients with severe aortic stenosis or ischemic heart disease.
• Avoid in pregnant women; switch to alternative therapy if pregnancy is detected.
• Not recommended in pediatric patients under 18 years of age unless prescribed by a specialist.

Storage Instructions Irbesartan (IRBEQ) 300mg Tablet 

• Store at temperatures not exceeding 30°C.
• Keep tablets in their original packaging to protect them from moisture.
• Keep out of reach of children.