About Fenofibrate (FENORIX) 200mg Capsule 100’s

Fenofibrate (FENORIX) 200mg Capsule 100’s is a lipid-modifying agent used primarily to reduce cholesterol and triglyceride levels in patients at risk of cardiovascular disease, particularly those with mixed dyslipidemia or severe hypertriglyceridemia. Each capsule contains 200mg of fenofibrate, a fibric acid derivative that works by activating peroxisome proliferator-activated receptors (PPARs), which play a crucial role in the regulation of lipid metabolism. This action helps decrease the levels of low-density lipoprotein cholesterol (LDL-C) and triglycerides while increasing high-density lipoprotein cholesterol (HDL-C), often referred to as “good cholesterol.”

Fenofibrate (FENORIX) 200mg Capsule 100’s is often used in conjunction with dietary and lifestyle changes to manage cholesterol levels in patients who are at increased risk of atherosclerosis, heart attacks, and strokes. It is particularly effective in patients with metabolic syndrome, type 2 diabetes, or obesity-related dyslipidemia. As part of a comprehensive lipid-lowering regimen, it helps improve long-term cardiovascular outcomes when used under proper medical guidance.

Indications of Fenofibrate (FENORIX) 200mg Capsule 100’s

• Treatment of primary hypercholesterolemia or mixed dyslipidemia as an adjunct to diet and other non-pharmacological treatments (e.g., exercise, weight loss).

• Management of severe hypertriglyceridemia, especially in patients at risk of pancreatitis.

• Adjunct therapy in type 2 diabetes mellitus patients with combined lipid abnormalities.

• For patients who are intolerant or unresponsive to statins alone, or in combination with statins under close supervision.

Dosage of Fenofibrate (FENORIX) 200mg Capsule 100’s

• Recommended dose: One 200mg capsule taken once daily.

• The capsule should be taken with food to enhance absorption.

• Dosage may be adjusted based on the patient’s lipid profile and renal function.

• Patients with mild to moderate renal impairment may require lower doses or close monitoring.

• Regular lipid profile assessments are necessary to determine the effectiveness of the therapy.

Do not self-adjust the dose or discontinue the medication without consulting a healthcare provider.

Side Effects of Fenofibrate (FENORIX) 200mg Capsule 100’s

Common side effects:

• Abdominal discomfort or indigestion

• Nausea

• Headache

• Elevated liver enzymes

• Back pain

Less common but serious side effects:

• Muscle pain, tenderness, or weakness (possible sign of myopathy or rhabdomyolysis)

• Gallstones (cholelithiasis)

• Pancreatitis

• Liver dysfunction or hepatitis

• Allergic reactions such as rash, hives, or swelling

Seek immediate medical attention if symptoms such as dark urine, yellowing of the skin/eyes, or unexplained muscle pain occur.

Contraindications of Fenofibrate (FENORIX) 200mg Capsule 100’s

• Known hypersensitivity to fenofibrate or any of its components

• Severe renal impairment (eGFR <30 mL/min/1.73 m²)

• Active liver disease, including cirrhosis or persistent liver function abnormalities

• Gallbladder disease or history of gallstones

• Pancreatitis, unless due to severe hypertriglyceridemia

• Pregnancy and breastfeeding

• Children and adolescents under 18 years of age

Precautions for Fenofibrate (FENORIX) 200mg Capsule 100’s

• Use with caution in patients taking statins, as combined therapy increases the risk of muscle toxicity.

• Regularly monitor liver function tests and renal function, especially during the first 12 months of therapy.

• Monitor for signs of muscle damage, especially in elderly patients or those with renal impairment.

• Ensure adequate hydration to support kidney function.

• Patients with hypothyroidism may be at increased risk of myopathy.

• Lifestyle and dietary modifications should continue during therapy for optimal results.

Storage of Fenofibrate (FENORIX) 200mg Capsule 100’s

• Store in a cool, dry place below 30°C.

• Keep capsules in their original packaging to protect from moisture and light.

• Do not use the medication past the expiration date.

• Keep out of reach of children and pets.