About Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

NEUROBE is a prescription-grade vitamin B complex injection designed to treat and prevent deficiencies of vitamins B1, B6, and B12. Each 3 mL ampoule contains:

• Thiamine Hydrochloride (Vitamin B1) – 100 mg

• Pyridoxine Hydrochloride (Vitamin B6) – 100 mg

• Cyanocobalamin (Vitamin B12) – 1,000 mcg

This combination supports nerve function, aids in the metabolism of carbohydrates, proteins, and fats, and is essential for red blood cell formation.

Indications of Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

NEUROBE is indicated for the treatment of conditions associated with vitamin B deficiencies, including:

• Peripheral neuritis and neuralgia

• Diabetic polyneuropathy

• Alcohol-induced neuropathies

• Post-infectious polyneuritis

• Myasthenia

• Paresthesia

• Atherosclerosis

• Wernicke’s encephalopathy

• Dermatitis and neurodermatitis

• Stomatitis and cheilitis

• Chronic alcohol abuse

• Anemia and asthenia

• Intoxications

Dosage and Administration of Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

• Route: Intramuscular (IM) injection, preferably deep intragluteal.

• Dosage: As prescribed by a healthcare professional, based on the severity of the deficiency and patient response.

Administration Instructions:

1. Ensure the ampoule is at room temperature before administration.

2. Use aseptic techniques to prevent contamination.

3. Inject the solution slowly into the muscle to minimize discomfort.

Contraindications of Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

NEUROBE should not be used in patients with:

• Hypersensitivity to any of the active ingredients or excipients.

• Children under 14 years of age due to high vitamin concentrations.

• Patients undergoing Levodopa therapy, as Vitamin B6 can interfere with its efficacy.

Side Effects of Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

While generally well-tolerated, some patients may experience:

• Injection site reactions (pain, redness, swelling)

• Allergic reactions (rash, itching, anaphylaxis)

• Gastrointestinal disturbances (nausea, vomiting)

• Neurological symptoms with prolonged high-dose use of Vitamin B6 (e.g., sensory neuropathy)

If any adverse reactions occur, discontinue use and consult a healthcare provider.

Precautions for Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

• Monitor patients for signs of hypersensitivity during initial administrations.

• Long-term use should be under medical supervision to prevent potential toxicity, especially from Vitamin B6.

• Use with caution in pregnant or breastfeeding women; consult a healthcare provider before use.

Storage of Vitamin B1 + B6 + B12 (NEUROBE) Ampoule 3mL x 10’s

• Store at temperatures not exceeding 30°C.

• Protect from light and moisture.

• Keep out of reach of children.

• Do not use if the solution is discolored or contains particles.