About Silver Sulfadiazine (FARADERM) 10mg/g Cream 30g

Silver Sulfadiazine (FARADERM) 10mg/g Cream is a topical antimicrobial cream widely used in the treatment and prevention of infections in burn wounds. Each gram of FARADERM contains 10mg of silver sulfadiazine, a sulfonamide antibiotic combined with silver ions, which work synergistically to combat a wide spectrum of gram-positive and gram-negative bacteria as well as some fungi. This makes it especially useful in minimizing infection risks associated with second- and third-degree burns, surgical wounds, ulcers, and skin grafts.

The silver component acts as a potent antimicrobial agent by disrupting bacterial cell walls and inhibiting DNA replication, while the sulfadiazine component impairs bacterial folic acid synthesis. This dual action not only prevents colonization but also treats active infections on the wound surface.

FARADERM is typically applied once or twice daily as a thin layer directly onto the affected area. It promotes healing, reduces pain, and minimizes the risk of systemic infection. It is suitable for use in hospitals, emergency rooms, burn units, and home care settings under medical supervision.

Indications of Silver Sulfadiazine (FARADERM) 10mg/g Cream 30g

• Treatment and prevention of infection in second- and third-degree burns

• Adjunctive treatment for skin ulcers, pressure sores, and donor or graft sites

• Management of minor cuts, abrasions, or skin infections at risk of bacterial contamination

Dosage and Administration of Silver Sulfadiazine (FARADERM) 10mg/g Cream 30g

• Clean the wound area before application

• Apply a thin layer (approximately 1/16 inch) of cream to cover the affected area

• Reapply 1–2 times daily or as directed by a healthcare professional

• Wounds may be left uncovered or covered with a sterile dressing

• Continue use until healing or skin grafting occurs

Contraindications of Silver Sulfadiazine (FARADERM) 10mg/g Cream 30g

• Hypersensitivity to sulfonamides or silver compounds

• Neonates and premature infants due to risk of kernicterus

• Patients with G6PD deficiency may be at higher risk of hemolysis

• Avoid use on large surface areas in pregnant women, especially near term

Side Effects of Silver Sulfadiazine (FARADERM) 10mg/g Cream 30g

Common side effects:

• Temporary burning or itching sensation

• Skin discoloration or staining

• Rash or irritation at application site

Rare but serious side effects:

• Allergic reactions (e.g., hives, swelling, anaphylaxis)

• Leukopenia (low white blood cell count)

• Methemoglobinemia (impaired oxygen delivery in blood)

• Systemic absorption in patients with large burn areas or impaired renal function

Precautions for Silver Sulfadiazine (FARADERM) 10mg/g Cream 30g

• Use with caution in patients with impaired liver or kidney function

• Monitor for signs of hypersensitivity, especially during initial use

• Not recommended for prolonged use on extensive burn areas without medical supervision

• May delay wound healing in some cases; periodic evaluation is essential