Povidone Iodine (ZETADONE) 10% Solution 120mL

About Povidone Iodine (ZETADONE) 10% Solution 120mL

Povidone Iodine (ZETADONE) 10% Solution 120mL is a powerful antiseptic solution designed for external use to prevent and treat infections. The solution contains 10% povidone-iodine, which is a combination of iodine and a carrier molecule (povidone) that helps iodine remain stable and increases its activity on the skin and mucous membranes.

• Formulation: Solution, typically in a liquid form for easy application to wounds, skin, and mucous membranes.
• Concentration: 10% povidone-iodine, providing a strong antiseptic effect against bacteria, viruses, fungi, and protozoa.
• Packaging: 1 Gallon (128 ounces), making it ideal for healthcare settings, large clinics, or hospitals where large quantities of antiseptic solution are required.
• Color: Typically brown or amber in color due to the iodine content.
• Action: Povidone-iodine releases iodine when in contact with tissue, which works as a broad-spectrum antimicrobial agent, killing a wide range of microorganisms.

Povidone Iodine (ZETADONE) 10% Solution 120mL is commonly used for wound cleansing, surgical site preparation, and general antiseptic use.

Indications of Povidone Iodine (ZETADONE) 10% Solution 120mL

• Preoperative Skin Antisepsis: To cleanse and disinfect the skin before surgical procedures, reducing the risk of infection.
• Wound Care: Used for cleaning and disinfecting minor cuts, scrapes, abrasions, and burns to prevent infection.
• Treatment of Infected Areas: For use in the management of infected wounds or areas prone to infection.
• Mucosal Disinfection: Can be used for disinfecting mucosal surfaces such as the mouth or throat for oral or throat infections (following appropriate dilution).
• Minor Skin Infections: Helps prevent and treat minor skin infections caused by bacteria, fungi, and viruses.
• General Antiseptic Use: Applied to a variety of external wounds and injured tissue to minimize microbial contamination and speed up the healing process.

Dosage of Povidone Iodine (ZETADONE) 10% Solution 120mL

• For Wound Cleaning:
  • Apply the solution directly to the affected area once or twice a day after cleaning the wound. Use a sterile cotton ball, gauze pad, or clean cloth to apply the solution.
  • Gently cleanse the wound, allowing the solution to remain in contact with the tissue for a few minutes. You can allow it to air dry for better antimicrobial action.
• For Preoperative Skin Antisepsis:
  • Apply to the surgical site 2-3 times prior to the procedure, starting from the center of the area and working outwards in a circular motion. Allow it to dry before proceeding with surgery.
• For Infected Skin Areas:
  • Apply a thin layer to the affected area once or twice daily, as needed. It may be left on to dry and form a protective layer over the infection.
• For Mucosal Use (such as mouth or throat infections):
  • Dilute the solution with water (typically 1:10 dilution) and use as a mouthwash or gargle.
• For General Antiseptic Use:
  • Use the solution as needed for cleaning skin and minor wounds.

Side Effects of Povidone Iodine (ZETADONE) 10% Solution 120mL

• Skin Irritation: Mild irritation, burning, or stinging at the application site is possible, especially if the area is sensitive or if the solution is used excessively.
• Allergic Reactions: Rare but serious allergic reactions can occur, including redness, itching, swelling, or blistering. In very rare cases, anaphylaxis may occur, which requires immediate medical attention.
• Staining: Povidone iodine can stain the skin, clothing, and surrounding surfaces, leaving a brownish color that can be difficult to remove.
• Dry Skin: Prolonged use on large areas of skin may lead to dryness or peeling, especially in people with sensitive skin.
• Thyroid Issues: Overuse or large-scale absorption can lead to iodine toxicity, which may affect thyroid function in susceptible individuals, particularly those with pre-existing thyroid problems.
• Systemic Absorption: Although rare, systemic absorption may occur, leading to symptoms such as nausea, vomiting, fever, and dizziness, especially if used on large areas or for extended periods.

Contraindications of Povidone Iodine (ZETADONE) 10% Solution 120mL

• Hypersensitivity to Iodine or Povidone: Individuals who are allergic to iodine or any other component of the formulation should avoid using this product.
• Avoid Use on Large Wounds or Burns: If used on large open wounds, burns, or broken skin, povidone iodine can be absorbed into the bloodstream, potentially leading to toxicity.
• Neonates and Infants: Povidone iodine should not be used on neonates (newborns) or infants, especially on large areas of the skin, as they are more susceptible to iodine toxicity, which can affect thyroid function and other metabolic processes.
• Thyroid Disease: Individuals with thyroid disorders, especially those with hyperthyroidism or a history of iodine sensitivity, should avoid using iodine-based products, as they may disrupt thyroid function.
• Pregnancy (in high doses): While topical use is generally considered safe during pregnancy, povidone-iodine should be used with caution, especially in large amounts or on broken skin, as iodine can be absorbed into the body. Always consult a healthcare provider before use in pregnant women.
• Avoid Use Near Eyes or Mucous Membranes: This solution should not be applied directly to the eyes or mucous membranes unless diluted, as it can cause irritation and damage to sensitive tissues.

Additional Notes

• Storage: Store the Povidone Iodine 10% Solution 120ml  in a cool, dry place, away from direct sunlight and heat. Keep the container tightly sealed to avoid contamination.
• Disposal: Dispose of any unused or expired product according to local regulations, especially considering its iodine content.
• Use as Directed: Always follow the dosage and usage instructions provided by your healthcare provider or as indicated on the product label. Do not use for prolonged periods without consulting a healthcare professional.

Storage 

• Store Povidone Iodine 10% Solution 120ml  at temperatures below 30°C to maintain potency.
• Keep the bottle tightly sealed to prevent contamination.
• Avoid direct sunlight and humidity exposure.