About Levofloxacin (QUINOGEN) 500mg Tablet 100’s

Levofloxacin (QUINOGEN) 500mg Tablet is a broad-spectrum antibiotic belonging to the fluoroquinolone class, used to treat a wide variety of bacterial infections. Each tablet contains 500 mg of Levofloxacin, an effective antibacterial agent that works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and repair. This mechanism halts bacterial growth and ultimately kills the bacteria.

QUINOGEN is indicated for use in adults and suitable adolescents with confirmed or suspected bacterial infections, including those affecting the respiratory tract, urinary tract, gastrointestinal system, and skin. It is commonly prescribed for community-acquired pneumonia, chronic bronchitis, urinary tract infections (UTIs), prostatitis, acute sinusitis, and certain types of skin and soft tissue infections. Due to its excellent tissue penetration and long half-life, it allows for once-daily dosing in many cases, promoting better patient compliance.

Levofloxacin is well absorbed orally and achieves high bioavailability, making it a practical option for both outpatient and hospital-based treatments. It is often chosen when switching from intravenous to oral therapy.

Indications of Levofloxacin (QUINOGEN) 500mg Tablet 100’s

• Community-acquired pneumonia

• Acute bacterial sinusitis

• Chronic bronchitis exacerbations

• Complicated and uncomplicated UTIs

• Acute pyelonephritis

• Chronic bacterial prostatitis

• Skin and soft tissue infections

• Inhalation anthrax (post-exposure prophylaxis)

Dosage and Administration of Levofloxacin (QUINOGEN) 500mg Tablet 100’s

• Typical adult dose: 500 mg once daily for 7–14 days, depending on the type and severity of the infection

• Renal impairment: Dosage adjustment may be required

• Tablets should be taken with or without food and swallowed whole with water. 

Important note: Avoid taking antacids, multivitamins, or supplements containing calcium, iron, or zinc within 2 hours before or after taking levofloxacin, as they may reduce absorption.

Contraindications of Levofloxacin (QUINOGEN) 500mg Tablet 100’s

• Hypersensitivity to Levofloxacin, other fluoroquinolones, or any excipients

• History of tendon disorders related to fluoroquinolone use

• Children and adolescents (except in specific, approved cases)

• Pregnant or breastfeeding women, unless clearly needed

Side Effects of Levofloxacin (QUINOGEN) 500mg Tablet 100’s

Common:

• Nausea

• Diarrhea

• Headache

• Dizziness

• Insomnia

Serious but rare:

• Tendon rupture (especially in the elderly or those on corticosteroids)

• Peripheral neuropathy

• QT prolongation and heart rhythm disturbances

• Central nervous system effects (seizures, agitation)

• Allergic reactions, including rash or anaphylaxis

Precautions of Levofloxacin (QUINOGEN) 500mg Tablet 100’s

• Use with caution in patients with renal impairment, epilepsy, cardiac arrhythmias, or diabetes

• Avoid excessive sun exposure; photosensitivity may occur

• Discontinue if experiencing tendon pain or signs of peripheral neuropathy

• Not recommended in growing children due to potential effects on developing cartilage

Storage Instructions of Levofloxacin (QUINOGEN) 500mg Tablet 100’s

• Store below 30°C

• Protect from light and moisture

• Keep out of reach of children