About Lactulose (EASELAC) 3.33g/5mL Solution 120mL

Lactulose (EASELAC) 3.33g/5mL Solution 120mL is an oral solution used primarily for the treatment of constipation and as an adjunct therapy in the management of hepatic encephalopathy. Each 5mL of solution contains 3.33 grams of lactulose, a synthetic disaccharide made from lactose that is not absorbed in the small intestine. Instead, it reaches the colon intact, where it is broken down by gut bacteria into low-molecular-weight organic acids that help retain water in the stool and acidify the contents of the colon.

This mechanism not only softens stools and promotes bowel movements but also reduces the absorption of ammonia in the colon, making it highly effective in preventing and treating hepatic encephalopathy. Lactulose (EASELAC) 3.33g/5mL Solution 120mL is suitable for both adults and children and is especially helpful in cases where a gentle, non-stimulant laxative is preferred.

Indications of Lactulose (EASELAC) 3.33g/5mL Solution 120mL

Lactulose (EASELAC) 3.33g/5mL Solution 120mL is indicated for the following conditions:

• Chronic or occasional constipation: To promote regular bowel movements and relieve discomfort from infrequent stools.

• Hepatic encephalopathy (HE): As an adjunct to therapy in patients with liver disease to reduce elevated blood ammonia levels, thereby preventing or managing episodes of hepatic coma.

• Bowel regulation: For patients with conditions requiring consistent soft stool, such as post-surgery or hemorrhoids.

Dosage of Lactulose (EASELAC) 3.33g/5mL Solution 120mL

Dosage should be individualized based on age, condition, and response to treatment.

For constipation:

• Adults: Start with 15–30 mL once daily, which may be adjusted to 10–25 mL once or twice daily depending on response.

• Children 7–14 years: 15 mL daily.

• Children 1–6 years: 5–10 mL daily.

• Infants under 1 year: Up to 5 mL daily.

For hepatic encephalopathy:

• Adults: Typically, 30–45 mL three to four times daily. The goal is to achieve two to three soft stools per day.

Lactulose can be taken with or without food. It may be mixed with water, juice, or milk to improve taste. The effect may take 24–48 hours to occur when used for constipation.

Side Effects of Lactulose (EASELAC) 3.33g/5mL Solution 120mL

Like all medications, Lactulose (EASELAC) 3.33g/5mL Solution 120mL may cause side effects in some users, though it is generally well tolerated.

Common side effects:

• Bloating

• Flatulence

• Abdominal cramping

• Mild nausea

Less common or serious side effects:

• Diarrhea (especially with high doses)

• Electrolyte imbalance (e.g., low potassium or high sodium levels) with prolonged use

• Dehydration

• Allergic reactions such as rash, itching, or swelling (rare)

If symptoms persist or worsen, consult a healthcare professional.

Contraindications of Lactulose (EASELAC) 3.33g/5mL Solution 120mL

Lactulose (EASELAC) 3.33g/5mL Solution 120mL is contraindicated in the following situations:

• Patients with galactosemia (a rare genetic metabolic disorder)

• Known hypersensitivity to lactulose or any component of the product

• Patients requiring a low-galactose or low-lactose diet

• Patients with gastrointestinal obstruction, perforation, or undiagnosed abdominal pain

Use caution in diabetic patients, as the solution may contain residual sugars such as lactose, galactose, and fructose.

Precautions for Lactulose (EASELAC) 3.33g/5mL Solution 120mL

Before taking Lactulose (EASELAC) 3.33g/5mL Solution 120mL, consider the following precautions:

• Monitor electrolyte levels in patients taking high doses or using long-term for hepatic encephalopathy.

• Use with caution in elderly patients or those prone to fluid/electrolyte imbalance.

• Diabetics should consult a doctor due to sugar content.

• Not to be used for more than 7 days without medical supervision if used solely for constipation.

• Consult a doctor if there is no bowel movement after 3 days of use.

Storage of Lactulose (EASELAC) 3.33g/5mL Solution 120mL

• Store at a temperature below 30°C.

• Do not refrigerate or freeze, as extreme cold may alter the solution’s consistency.

• Keep the bottle tightly closed when not in use.

• Protect from light and moisture.

• Keep out of reach of children.