About Gliclazide (ZEBET) 80mg Tablet

Gliclazide (ZEBET) 80mg Tablet is a modified-release oral antidiabetic medication used for the management of type 2 diabetes mellitus in adults. It belongs to the sulfonylurea class of drugs and helps control blood sugar levels by stimulating insulin secretion from the pancreas. The modified-release (MR) formulation ensures a steady and prolonged effect, allowing for once-daily dosing and improved glycemic control throughout the day. It is typically used as part of a broader diabetes management plan that includes diet, exercise, and possibly other antidiabetic medications.

Indications of Gliclazide (ZEBET) 80mg Tablet

• For the treatment of type 2 diabetes mellitus in adults when diet, physical activity, and weight reduction alone do not provide adequate glycemic control.

• May be used alone (monotherapy) or in combination with other antidiabetic agents such as metformin, alpha-glucosidase inhibitors, or insulin.

• Helps reduce the risk of diabetes-related complications by maintaining consistent blood glucose levels.

Dosage of Gliclazide (ZEBET) 80mg Tablet

• The usual starting dose is 30 mg once daily, preferably taken with breakfast.

• Dose may be adjusted based on individual blood glucose response, up to a maximum of 120 mg daily.

• Typical Dose: 80mg once or twice daily, preferably with meals.

• Dosage adjustments may be required based on blood glucose monitoring and individual response.

   

  Side Effects of Gliclazide (ZEBET) 80mg Tablet

Like all medications, Gliclazide (ZEBET) 80mg Tablet may cause side effects, although not everyone experiences them.

Common side effects:

• Hypoglycemia (low blood sugar), especially if meals are skipped or delayed

• Dizziness or headache

• Nausea or upset stomach

• Weight gain

Less common or rare side effects:

• Allergic skin reactions (rash, itching)

• Liver enzyme abnormalities

• Visual disturbances (due to fluctuations in blood sugar)

• Blood disorders such as anemia, leukopenia, or thrombocytopenia (rare)

Seek medical attention immediately if symptoms of severe hypoglycemia or allergic reactions occur.

Precautions for Gliclazide (ZEBET) 80mg Tablet

• Not suitable for use in type 1 diabetes or diabetic ketoacidosis.

• Use with caution in elderly patients or those with kidney or liver impairment.

• Alcohol consumption can increase the risk of hypoglycemia and should be minimized.

• Patients should be educated on the signs and management of low blood sugar.

• Regular blood glucose monitoring is essential, especially when used with other antidiabetic agents.

Contraindications of Gliclazide (ZEBET) 80mg Tablet

• Hypersensitivity to Gliclazide or any sulfonylureas/sulfonamides

• Type 1 diabetes mellitus

• Diabetic ketoacidosis or pre-coma diabetic states

• Severe renal or hepatic impairment

• Pregnancy and breastfeeding

• Use of miconazole (may increase risk of hypoglycemia)

Storage of Gliclazide (ZEBET) 80mg Tablet

Store in a cool, dry place at temperatures not exceeding 30°C. Keep in original packaging, away from moisture and direct sunlight.
Keep out of reach of children. Do not use beyond the expiry date indicated on the packaging.