About Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension 50mL

Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension 50mL is a second-generation cephalosporin antibiotic specially formulated for pediatric use. Once reconstituted, it becomes an oral suspension with a pleasant taste that ensures better compliance among children. SQCEF effectively treats a wide range of bacterial infections, including respiratory tract, ear, urinary, skin, and soft tissue infections. It offers broad-spectrum antibacterial coverage against both gram-positive and gram-negative organisms, making it a trusted choice among healthcare professionals. This product is manufactured with strict quality standards to ensure safety and efficacy in young patients.

Indication of Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension

• Upper respiratory tract infections: including pharyngitis, tonsillitis, and sinusitis

• Lower respiratory tract infections, such as bronchitis and community-acquired pneumonia

• Acute otitis media (ear infections)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections, such as impetigo and infected wounds

• Early Lyme disease (in children 2 years and older)

Contraindication of Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension

• Known hypersensitivity to cephalosporin antibiotics

• Severe allergic reaction (e.g., anaphylaxis) to penicillin or other beta-lactam antibiotics

• History of antibiotic-associated colitis or other serious gastrointestinal disorders

Dosage and Administration of Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension

Reconstitution Instructions:

• Add a total of 37 mL of distilled water to the bottle in two portions.

• Shake well after each addition until a uniform suspension is achieved.

• The reconstituted suspension provides 50 mL containing 125mg of cefuroxime per 5 mL.

Pediatric Dosage:

• Children: 20 to 30 mg/kg/day, divided into two doses every 12 hours, depending on the severity and type of infection.

• The maximum daily dose should be guided by a healthcare provider.

• Shake well before each use.

• Administer with a calibrated spoon or oral syringe.

• Complete the full course of treatment, even if symptoms improve early.

Precautions and Warnings of Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension

• Use only under medical supervision. Misuse may lead to antibiotic resistance.

• Cefuroxime should not be used to treat viral infections (e.g., flu, colds).

• Monitor patients for signs of hypersensitivity, including rash, itching, or anaphylactic reactions.

• Discontinue use immediately if Clostridioides difficile-associated diarrhea (CDAD) or severe gastrointestinal symptoms occur.

• Use with caution in patients with renal impairment, and dose adjustments may be required.

• Long-term use may result in the overgrowth of non-susceptible organisms, such as Candida.

Side Effects of Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension

• Gastrointestinal: Nausea, vomiting, abdominal pain, and diarrhea

• Skin reactions: Rash, urticaria (hives), or pruritus (itching)

• Central Nervous System: Headache

• Others: Transient increases in liver enzyme levels, positive Coombs’ test (without hemolysis)

Seek immediate medical attention if the patient experiences signs of serious allergic reactions, including swelling of the face/lips, difficulty breathing, or severe skin rashes.

Storage Instruction for Cefuroxime (SQCEF) 125mg/5mL Powder for Suspension

• Before reconstitution: Store the dry powder below 30°C, protected from light and moisture.

• After reconstitution: Store the suspension in the refrigerator at 2°C to 8°C.

• Use within 7 days of reconstitution.

• Do not freeze.

• Keep out of reach of children.